Thoracic Air Leak Syndrome, Pulmonary Aspergillosis, and COVID-19 Pneumonia After Allogeneic Stem Cell Transplantation in a Child With Myelodysplastic Syndrome
| Autor: | Ayse Tana Aslan, Serap Kirkiz, Tayyibe Sever, Ali Çelik, Zühre Kaya, Anil Tapisiz, Ülker Koçak, Tugba Gursoy, İsmail Akdulum, Melis Deniz |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Adolescent Coronavirus disease 2019 (COVID-19) medicine.medical_treatment Pneumonia Viral Graft vs Host Disease Bronchiolitis obliterans Hematopoietic stem cell transplantation Risk Factors Humans Medicine SARS-CoV-2 business.industry Hematopoietic Stem Cell Transplantation COVID-19 Hematology Prognosis medicine.disease Surgery Transplantation Pneumonia surgical procedures operative Graft-versus-host disease Pulmonary Emphysema Oncology Myelodysplastic Syndromes Concomitant Pediatrics Perinatology and Child Health Female Pulmonary Aspergillosis Stem cell business |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 44:e474-e478 |
| ISSN: | 1077-4114 |
| Popis: | Thoracic air leak syndromes (TALS) are very rare among the noninfectious pulmonary complications (PCs). They can either be idiopathic or have several risk factors such as allogeneic hematopoietic stem cell transplantation (allo-HSCT), graft versus host disease and rarely pulmonary aspergillosis. We present a 14-year-old girl with hypoplastic myelodysplastic syndrome who developed graft versus host disease on day 60, TALS on day 150, bronchiolitis obliterans syndrome on day 300, pulmonary aspergillosis on day 400 and COVID-19 pneumonia on day 575 after allo-HSCT. This is the first report of a child who developed these subsequent PCs after allo-HSCT. Therefore, the manifestations of these unfamiliar PCs like TALS and COVID-19 pneumonia, and concomitant pulmonary aspergillosis with management options are discussed. |
| Databáze: | OpenAIRE |
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