Barotaxis: how cells live and move under pressure
| Autor: | Ana-Maria Lennon-Duménil, Hélène D. Moreau |
|---|---|
| Přispěvatelé: | Immunité et cancer (U932), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), MOREAU, Hélène |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Chemokine
[SDV.IMM] Life Sciences [q-bio]/Immunology macropinocytosis environmental cues barotaxis Cell migration Cell Biology [SDV.BC]Life Sciences [q-bio]/Cellular Biology Biology Hydraulic resistance immunity Immune system Immunity Cell Movement Cancer cell biology.protein [SDV.IMM]Life Sciences [q-bio]/Immunology Chemokines chemotaxis Neuroscience Process (anatomy) [SDV.BC] Life Sciences [q-bio]/Cellular Biology cell guidance |
| Zdroj: | Current Opinion in Cell Biology Current Opinion in Cell Biology, Elsevier, 2021, 72, pp.131-136. ⟨10.1016/j.ceb.2021.07.006⟩ |
| ISSN: | 0955-0674 |
| DOI: | 10.1016/j.ceb.2021.07.006⟩ |
| Popis: | International audience; Cell migration is an essential process that controls many physiological functions ranging from development to immunity. In vivo, cells are guided by a combination of physical and chemical cues. Chemokines have been the center of attention for years, but the role of physical properties of tissues has been under-investigated. This despite the fact that these properties can be drastically modified in pathology. Here, we discuss the role of one important tissue physical property, hydraulic resistance, in cell guidance, a phenomenon referred to as barotaxis, and describe the underlying physical principles and molecular mechanisms. Finally, we speculate on the putative role of barotaxis in physiological processes involving immune and cancer cells. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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