Dynamics of Renin, Angiotensin II, and Angiotensin (1–7) during Pregnancy and Predisposition to Hypertension-Associated Complications
| Autor: | T. Yu. Ivanets, A. O. Karapetyan, N. V. Nizyaeva, O. R. Baev, A. Yu. Romanov, G. V. Khlestova |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
0301 basic medicine medicine.medical_specialty Blood Pressure 030204 cardiovascular system & hematology Normal pregnancy General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Pregnancy Internal medicine Renin Renin–angiotensin system medicine Humans Vasoconstrictor Agents Angiotensin 1 business.industry Angiotensin II General Medicine Middle Aged medicine.disease Peptide Fragments 030104 developmental biology Endocrinology Hypertension Gestation Female Angiotensin I business |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 165:438-439 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-018-4188-5 |
| Popis: | Changes in the levels of rennin, angiotensin II, and angiotensin (1-7) were studied during normal pregnancy. The blood was taken on gestation days 140-237 and 238-280. No significant changes in renin concentration were observed during normal pregnancy (p=0.423). The level of angiotensin II increased during normal pregnancy from 9.7±1.2 to 14.7±1.9 pg/ml (p=0.019). On the contrary, angiotensin (1-7) concentration decreased from 771.1±44.2 to 390.7±13.9 pg/ml (p |
| Databáze: | OpenAIRE |
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