Socioeconomic deprivation and the burden of head and neck cancer-Regional variations of incidence and mortality in Merseyside and Cheshire, North West, England
| Autor: | Ann Dingle, Sue Povall, Richard Shaw, Andrew Schache, David Taylor-Robinson, Joseph Rylands, Ian Hodge, Terry Jones, Jill Oakley, Yvonne Daley, Ruth du Plessis, Paul Wright, Bilal G. Taib |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult Male Longitudinal study medicine.medical_specialty Population 03 medical and health sciences 0302 clinical medicine Age Distribution Cost of Illness medicine Humans Sex Distribution education Socioeconomic status Disease burden Aged Retrospective Studies Aged 80 and over education.field_of_study business.industry Mortality rate Incidence (epidemiology) Public health Incidence Head and neck cancer Retrospective cohort study General Medicine Health Status Disparities Middle Aged medicine.disease Survival Rate 030104 developmental biology Oncology Otorhinolaryngology England Socioeconomic Factors North west Head and Neck Neoplasms 030220 oncology & carcinogenesis Optometry Surgery Female business Demography |
| Zdroj: | Clinical Otolaryngology |
| ISSN: | 1749-4486 |
| Popis: | Objectives The aim of this longitudinal study was to examine the distribution of head and neck cancer (HANC) disease burden across the region comparing it to national trends. Design We undertook a retrospective study of routine data combining it with indicators of deprivation and lifestyle at small geographical areas within the 9 Local Authorities (LAs) of Merseyside and Cheshire Network (MCCN) for head and neck cancers. Data from the North West of England and England were used as comparator regions. Setting This research was undertaken by the Cheshire and Merseyside Public Health Collaborative, UK. Participants The Merseyside and Cheshire region serves a population of 2.2 million. Routine data allowed us to identify HANC patients diagnosed with cancers coded ICD C00-C14 and C30-C32 within 3 cohorts 1998-2000, 2008-2010 and 2009-2011 for our analysis. Main outcome measures Directly age-standardised incidence rates and directly age-standardised mortality rates in the LAs and comparator regions were measured. Lifestyle and deprivation indicators were plotted against them and measured by Pearson's correlation coefficients. Results The incidence of head and neck cancer has increased across the region from 1998-2000 to 2008-2010 with a peak incidence for Liverpool males at 35/100 000 population. Certain Middle Super Output Areas contribute disproportionately to the significant effect of incidence and mortality within LAs. Income deprivation had the strongest correlation with incidence (r = .59) and mortality (r = .53) of head and neck cancer. Conclusion Our study emphasises notable geographical variations within the region which need to be addressed through public health measures. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text