Motor imagery in bipolar depression with slowed movement
| Autor: | Christoffer Rahm, Mats Adler, Lars-Olof Wahlund, Björn Wahlund, Mikael Landén, Tomas Jonsson, Maria Wiberg-Kristoffersen, Benny Liberg |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Bipolar Disorder Movement Posterior parietal cortex Prefrontal Cortex Gyrus Cinguli Premotor cortex Motor imagery Cortex (anatomy) Parietal Lobe medicine Limbic System Humans Prefrontal cortex Cerebrum Default mode network Aged Movement Disorders medicine.diagnostic_test Functional Neuroimaging Motor Cortex Middle Aged Magnetic Resonance Imaging Psychiatry and Mental health medicine.anatomical_structure Posterior cingulate Female Functional magnetic resonance imaging Psychology Neuroscience |
| Zdroj: | The Journal of nervous and mental disease. 201(10) |
| ISSN: | 1539-736X |
| Popis: | We hypothesized that motor retardation in bipolar depression is mediated by disruption of the pre-executive stages of motor production. We used functional magnetic resonance imaging to investigate neural activity during motor imagery and motor execution to elucidate whether brain regions that mediate planning, preparation, and control of movement are activated differently in subjects with bipolar depression (n = 9) compared with healthy controls (n = 12). We found significant between-group differences. During motor imagery, the patients activated the posterior medial parietal cortex, the posterior cingulate cortex, the premotor cortex, the prefrontal cortex, and the frontal poles more than the controls did. Activation in the brain areas involved in motor selection, planning, and preparation was altered. In addition, limbic and prefrontal regions associated with self-reference and the default mode network were altered during motor imagery in bipolar depression with motor retardation. Language: en |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|