Contractile pattern in acutely hibernating myocardium
| Autor: | Knut Arvid Kirkebøen, Arnfinn Ilebekk, Jon Offstad, K. Lande |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Time Factors Contraction (grammar) Myocardial ischemia Swine Physiology Myocardial Ischemia Ischemia Oxygen Consumption Myocardial oxygen consumption Coronary Circulation Physiology (medical) Internal medicine medicine Animals Humans Myocardial Stunning Hibernating myocardium Vascular disease business.industry Myocardium Stunning Blood flow medicine.disease Myocardial Contraction Cardiology medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Basic Research in Cardiology. 90:16-18 |
| ISSN: | 1435-1803 0300-8428 |
| Popis: | In the hibernating myocardium contractile function and energy consumption are downregulated in response to reduced coronary blood flow (2, 4, 7 – 9). Thus, the myocardium may survive prolonged periods of reduced blood flow without overt signs of ischemia, and it may regain normal contractile function when blood flow restrictions are terminated. The mechanism for this phenomenon is presently unknown, but to get insight into the mechanism involved, it is important to characterize all aspects of it as closely as possibly. Since a direct comparison of regional contractile pattern in acutely hibernating and stunned myocardium has not been reported, we here present such a comparison. We also relate changes in the regional contractile pattern to alterations in local myocardial oxygen consumption (MVO2). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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