Specific Reaction Patterns to Distinct Positive Emotional Cues Related to Incentive Motivation in Dependence of the Taq1A-Polymorphism: Molecular Genetic Associations of Early and Late Event-Related Potentials
| Autor: | Catrin Wielpuetz, Phillip Grant, Erik M. Müller, Roman Osinsky, Aisha J.L. Munk, Jürgen Hennig |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Adolescent media_common.quotation_subject Closeness Emotions Lust Protein Serine-Threonine Kinases Polymorphism Single Nucleotide 050105 experimental psychology Developmental psychology 03 medical and health sciences Young Adult 0302 clinical medicine Event-related potential Genotype Humans 0501 psychology and cognitive sciences Allele Evoked Potentials Biological Psychiatry Alleles Genetic Association Studies media_common Cerebral Cortex ANKK1 Motivation Receptors Dopamine D2 05 social sciences Electroencephalography Anticipation Psychiatry and Mental health Neuropsychology and Physiological Psychology Stroop Test Cues Psychology 030217 neurology & neurosurgery Stroop effect |
| Zdroj: | Neuropsychobiology. 73(1) |
| ISSN: | 1423-0224 |
| Popis: | Background/Aims: Early and late event-related potential (ERP) responses, representing early subconscious and late motivational processes, were recorded for positive emotional words related to ‘wanting' and ‘liking', in dependence of the dopamine-related Taq1A genotype (ANKK1/DRD2). Research suggests that ‘wanting' as opposed to ‘liking' is related to dopaminergic processes. Therefore, it was hypothesized that risk allele carriers of the Taq1A polymorphism exhibit late ERP changes in reaction to words representing incentive motivation, i.e. ‘wanting' (word categories ‘lust' and ‘anticipation'), but not to words representing ‘liking' (‘closeness'). Methods: Seventy-two male participants performed an emotional-word Stroop task during EEG recording and were genotyped according to the Taq1A polymorphism of ANKK1/DRD2. Results: Positive emotional words related to anticipation and lust revealed blunted responses in the late positive potential (LPP) in carriers of the A1 allele, an effect absent in response to ‘liking'-related words. These differences were not evident in the earlier posterior negativity (EPN). Conclusion: As no differences in dependence of the Taq1A genotype were observed in reaction to ‘wanting'- and ‘liking'-related words in the EPN, but merely in the LPP, it can be assumed that incentive-motivational stimuli only modify motivation-related ERP responses in carriers of the A1 allele of the Taq1A polymorphism, indicating the role of dopamine in late ERP components. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|