Toe metastasis: A rare pattern of cervical cancer spread

Autor: Marcia A. Ciccone, Charlotte L. Conturie, Koji Matsuo, Cassie M. K. L. Lee
Jazyk: angličtina
Předmět:
Zdroj: Gynecologic Oncology Case Reports
ISSN: 2211-338X
DOI: 10.1016/j.gynor.2013.12.004
Popis: BackgroundCervical cancer is locally invasive, spreading primarily throughdirect extension. Lymphatic spread to regional pelvic nodes is lesscommon, and hematogenous spread occurs even less frequently,often occurring in advanced stages of cervical cancer with highgrade tumors that is responsible for metastases to lungs, liver,spleen,brain,andbone(Agarwaletal.,2002).Accordingly,boneme-tastases most commonly involve direct and lymphatic spread to thepelvis and lumbar spine (Dewdney and Selvarajah, 2010). Distal ap-pendicular skeletal metastases, attributable to hematogenous dis-ease dissemination, are rare.Here, we report two cases of squamous cell carcinoma of the cervixmetastatic to the toe, causing pain, edema, and erythema, symptomswhich can mimic infectious etiology. Because toe metastases are rare,both cases were initially thought to be of infectious origin, highlightingthe importance of awareness of this site of metastases.
Databáze: OpenAIRE