The Whole Genome Sequence of Sphingobium chlorophenolicum L-1: Insights into the Evolution of the Pentachlorophenol Degradation Pathway
| Autor: | Hajnalka E. Daligault, Pernilla Turner, Shelley D. Copley, Matt Nolan, Miriam Land, Joseph Rokicki |
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| Rok vydání: | 2011 |
| Předmět: |
tetrachlorobenzoquinone reductase
Pentachlorophenol enzyme evolution Biology Hydroxylation biodegradation Genome Evolution Molecular 03 medical and health sciences chemistry.chemical_compound Plasmid Bacterial Proteins Genetics pentachlorophenol hydroxylase Quinone Reductases Gene Research Articles Conserved Sequence Ecology Evolution Behavior and Systematics 030304 developmental biology Sphingobium chlorophenolicum Whole genome sequencing 0303 health sciences Base Sequence 030306 microbiology Chromosome Mapping Sequence Analysis DNA Chromosomes Bacterial biology.organism_classification tetrachlorohydroquinone dehalogenase 3. Good health Sphingomonadaceae Biodegradation Environmental chemistry Genes Bacterial Horizontal gene transfer Sphingobium japonicum horizontal gene transfer Replicon Genome Bacterial Metabolic Networks and Pathways |
| Zdroj: | Genome Biology and Evolution |
| ISSN: | 1759-6653 |
| DOI: | 10.1093/gbe/evr137 |
| Popis: | Sphingobium chlorophenolicum Strain L-1 can mineralize the toxic pesticide pentachlorophenol (PCP). We have sequenced the genome of S. chlorophenolicum Strain L-1. The genome consists of a primary chromosome that encodes most of the genes for core processes, a secondary chromosome that encodes primarily genes that appear to be involved in environmental adaptation, and a small plasmid. The genes responsible for degradation of PCP are found on chromosome 2. We have compared the genomes of S. chlorophenolicum Strain L-1 and Sphingobium japonicum, a closely related Sphingomonad that degrades lindane. Our analysis suggests that the genes encoding the first three enzymes in the PCP degradation pathway were acquired via two different horizontal gene transfer events, and the genes encoding the final two enzymes in the pathway were acquired from the most recent common ancestor of these two bacteria. |
| Databáze: | OpenAIRE |
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