Efficacy of 694-nm Q-Switched Ruby Fractional Laser Treatment of Melasma in Female Korean Patients
| Autor: | Chang Kyun Lee, Woo Sun Jang, Myeung Nam Kim, Beom Joon Kim |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
medicine.medical_specialty Melasma Fractional laser Treatment outcome Lasers Solid-State Dermatology Severity of Illness Index Melanosis law.invention Low-Level Light Therapy law Humans Medicine integumentary system business.industry Ruby laser General Medicine Middle Aged Laser medicine.disease Treatment Outcome Patient Satisfaction Female Surgery Dose Fractionation Radiation business |
| Zdroj: | Dermatologic Surgery. 37:1133-1140 |
| ISSN: | 1076-0512 |
| DOI: | 10.1111/j.1524-4725.2011.02018.x |
| Popis: | Melasma is a common acquired symmetrical hypermelanosis of sun-exposed areas of the skin. Although the classical Q-switched ruby laser (QSRL) has been used successfully for the removal of tattoos and for the treatment of cutaneous pigmented lesions, its efficacy for melasma remains controversial.We used repeat low-dose fractional QSRL treatment for melasma and analyzed the clinical results.Fifteen Korean women with melasma were enrolled. Each patient received six low-dose fractional QSRL treatments to the face at 2-week intervals. Two investigators independently evaluated Melasma Area and Severity Index (MASI) scores before each session and 4 and 16 weeks after the final session. The intensities of pigmentation and erythema were assessed by measuring skin reflectance using a tristimulus color analyzer.Mean MASI score decreased from 15.1 ± 3.3 before treatment to 10.6 ± 3.9 16 weeks after the final treatment. The lightness of pigmentation (L-value) increased from 56.6 ± 3.5 before treatment to 59.9 ± 2.8 16 weeks after the final treatment.Multiple treatment sessions of low-dose fractional QSRL may be an effective strategy for the treatment of dermal or mixed-type melasma. |
| Databáze: | OpenAIRE |
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