Epidemiologic changes in bloodstream infections in Andalucía (Spain) during the last decade
| Autor: | C. Herrero Rodríguez, J F Lanz García, M Guzman García, Fátima Galán-Sánchez, C Natera Kindelan, A Del Arco Jiménez, P.M. Martínez Pérez-Crespo, Probac Reipi, Geih-Seimc, I M Reche Molina, D. Vinuesa García, J M Sánchez Calvo, León E, Jesús Rodríguez-Baño, J M Reguera Iglesias, Luis Eduardo López-Cortés, P Retamar-Gentil, B Becerril Carral, I Pérez Camacho, Antonio Sánchez-Porto, Inmaculada López-Hernández |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Male medicine.medical_specialty Multivariate analysis Epidemiology 030106 microbiology Population Bloodstream infection 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Sepsis Medicine Humans 030212 general & internal medicine Prospective Studies Mortality Aetiology skin and connective tissue diseases education Aged education.field_of_study business.industry Incidence (epidemiology) Incidence General Medicine Odds ratio Bacterial Infections Middle Aged Confidence interval Infectious Diseases Logistic Models Mycoses Spain Relative risk Bacteraemia Female sense organs Bloodstream infections business Cohort study |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | [Objectives]: During the last decade, some changes in the epidemiology of invasive infections have been reported; however, specific studies with patient-level data are scarce. The aim of this study was to describe and evaluate the epidemiologic changes in bloodstream infections (BSI) during the last decade in Andalucía, Spain. [Methods]: Data from two prospective cohorts of BSI in adults with the same methodology performed 10 years apart in 11 hospitals (eight tertiary and three community) in Andalucía, Spain, were compared; the 2006–7 cohort study was performed between October 2006 and March 2007, and the 2016–17 cohort study was performed between October 2016 and March 2017. Population-based incidence rates were calculated and extrapolated for 1 year. Relative risk ratios were calculated between the 2 periods. Multivariate analyses were performed by logistic regression. [Results]: Overall, 1262 episodes of BSI were included, 563 (44.6%) in 2006–7 and 699 (55.3%) in 2016–17. Multivariate models selected the following changes in patients' features in 2016–17, after controlling for type of acquisition: higher age (odds ratio (OR) = 1.02; 95% confidence interval [CI] 1.01–1.03), lower urinary catheter (OR = 0.37; 95% CI, 0.26–0.48) and lower Pitt score (OR = 0.76; 95% CI, 0.71–0.82). Adjusted estimations considering patients' features and exposure to procedures showed a reduction in coagulase-negative staphylococci (OR = 0.47; 95% CI, 0.32–0.69), and an increase in Proteus spp. (OR = 3.12; 95% CI, 1.18–8.23) and Candida spp. (OR = 3.01; 95% CI, 1.03–8.86). [Conclusions]: We found relevant epidemiologic changes in BSI in our area, including rates, frequency of acquisition types, changes in patient's profiles and aetiologic agents. |
| Databáze: | OpenAIRE |
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