Prognostic factors of pacing-induced cardiomyopathy
| Autor: | Hong Zhang, Yu-Jie Zhou, Yu-Jie Zeng, Ning-Ning Wang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Cardiomyopathy lcsh:Medicine Ventricular Function Left 03 medical and health sciences QRS complex 0302 clinical medicine Internal medicine medicine Humans Right ventricular pacing Retrospective Studies Heart Failure Univariate analysis Ejection fraction Proportional hazards model business.industry Hazard ratio lcsh:R Cardiac Pacing Artificial Stroke Volume General Medicine Original Articles medicine.disease Prognosis Confidence interval Pacing-induced cardiomyopathy 030220 oncology & carcinogenesis Heart failure Cardiology cardiovascular system business Cardiomyopathies 030217 neurology & neurosurgery |
| Zdroj: | Chinese Medical Journal Chinese Medical Journal, Vol 133, Iss 13, Pp 1533-1539 (2020) |
| ISSN: | 2542-5641 0366-6999 |
| Popis: | Background:. The detrimental outcomes of right ventricular pacing on left ventricular electromechanical function ultimately result in heart failure, a phenomenon termed pacing-induced cardiomyopathy (PICM) in clinical research. This study aimed to validate prognostic factors that can be used to identify patients with higher susceptibility to progress to the stage of cardiomyopathy before pacemaker implantation. Methods:. This observational analysis enrolled 256 patients between January 2013 and June 2016, 23 (8.98%) of whom progressed to PICM after 1 year of follow-up. A Cox proportional hazard model was used to analyze the prognostic factors associated with PICM. Dose-response analysis was used to evaluate the relationship between significant indicators in multifactor analysis and PICM. Results:. The mean values of left ventricular ejection fraction before and after pacemaker implantation in 23 patients diagnosed with PICM were 62.3% and 42.7%, respectively. Univariate analysis showed that sex, atrio-ventricular block, paced QRS duration, and ventricular pacing percentage were significantly associated with PICM. In the multivariate analysis, male sex (hazard ratio: 1.20, 95% confidence interval [CI]: 1.09–1.33, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|