Effects of surfactants on glucosyltransferase production and in vitro sucrose-dependent colonization by Streptococcus mutans
| Autor: | Kazuo Fukushima, Yukihide Tomita, Takeo Takeuchi, Takuji Ikemi, Noriko Shinozaki, Tamae Watanabe, Akio Nanbu |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Sucrose
food.ingredient Octoxynol Dental Plaque Polysorbates Polysaccharide Lecithin Bacterial Adhesion Microbiology Streptococcus mutans Surface-Active Agents chemistry.chemical_compound Glucosyltransferases food stomatognathic system Pulmonary surfactant Humans Glucans General Dentistry chemistry.chemical_classification biology Chemistry Polysaccharides Bacterial Cell Biology General Medicine biology.organism_classification In vitro stomatognathic diseases Solubility Otorhinolaryngology Phosphatidylcholines biology.protein Glucosyltransferase |
| Zdroj: | Archives of Oral Biology. 43:735-740 |
| ISSN: | 0003-9969 |
| Popis: | The presence of Tween 80 in media was associated with a significant increase in three glucosyltransferases(GTFs)(I, SI and S), especially GTF-I, produced by Streptococcus mutans strain PS14, indicating that the surfactant is a major cause of the enhanced GTF production observed in cultures in M4 medium. Lecithin and Tween 20 also enhanced GTF-I production, while Triton X-100 depressed it. At a lot concentration of 0.00125%, Tween 80 enhanced markedly only GTF-I production and its effect reached maximum at a concentration of 0.0025%. Water-insoluble glucan synthesis and artificial plaque formation (in vitro sucrose-dependent colonization) by PS14 were significantly enhanced by the addition of Tween 80 at concentrations over 0.00125%. These results suggest that surfactants might vary the cariogenic potential of Strep. mutans even at low concentrations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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