Preventive effect of pectic oligosaccharides on acute colitis model mice: modulating epithelial barrier, gut microbiota and Treg/Th17 balance

Autor:	Haoyu Wang, Nian Liu, Zizhen Yang, Kunyi Zhao, Hao Pang, Kaidi Shao, Zihan Zhou, Shangyong Li, Ningning He
Rok vydání:	2022
Předmět:	Dietary Fiber Colon Dextran Sulfate Oligosaccharides General Medicine Colitis T-Lymphocytes Regulatory Gastrointestinal Microbiome Mice Inbred C57BL Disease Models Animal Mice Animals Cytokines Pectins Th17 Cells Colitis Ulcerative Food Science
Zdroj:	Food & Function. 13:9999-10012
ISSN:	2042-650X 2042-6496
DOI:	10.1039/d2fo01448c
Popis:	Pectin as a dietary fiber supplement has shown emerging potential in clinical ulcerative colitis (UC) adjuvant therapy. In this study, the preventive and prebiotic effects of enzymatically degraded pectic oligosaccharides (POS) were further explored in dextran sodium sulfate (DSS)-induced colitis mice. The POS supplement (400 mg kg
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d641a23e2cfb0477853ae286132198dd https://doi.org/10.1039/d2fo01448c Zobrazit plný text záznamu