Reduction of insulin dose on changing diabetic children from standard to monocomponent insulins
Autor: | M A Smith, J D Baum, N K Griffin |
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Rok vydání: | 1979 |
Předmět: |
Male
Glycosuria medicine.medical_specialty Adolescent medicine.medical_treatment Urine Insulin dose Drug Administration Schedule Excretion Diabetes mellitus Internal medicine Diabetes Mellitus medicine Humans Insulin Child Dose-Response Relationship Drug business.industry medicine.disease Diabetes Mellitus Type 1 Endocrinology Child Preschool Pediatrics Perinatology and Child Health Female sense organs medicine.symptom business Urine glucose Research Article Diabetic control |
Zdroj: | Archives of Disease in Childhood. 54:123-126 |
ISSN: | 1468-2044 0003-9888 |
DOI: | 10.1136/adc.54.2.123 |
Popis: | 21 diabetic children requiring greater than 50 units of standard insulin daily were changed to a monocomponent insulin. During the 3 months before the change the insulin dose had risen significantly from a mean of 70 to a mean of 77 units daily. During the 3 months after the change the dose fell significantly to a mean of 53 units daily. This decrease in insulin requirement was associated with a general improvement in diabetic control. This was assessed clinically and measured in 10 children by an analysis of home urine tests and in 8 children by an analysis of 24-hour urine glucose excretion. |
Databáze: | OpenAIRE |
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