Genetic diversity of Toxoplasma gondii isolates from rodents in the world: A systematic review
| Autor: | Shahabeddin Sarvi, Seyed Abdollah Hosseini, Ahmad Daryani, Tahereh Mikaeili Galeh |
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| Rok vydání: | 2021 |
| Předmět: |
Genotype
040301 veterinary sciences Population structure Rodentia Biology Rodent Diseases 0403 veterinary science 03 medical and health sciences parasitic diseases medicine Animals Parasite hosting Genotyping 030304 developmental biology Genetics 0303 health sciences Genetic diversity General Veterinary General Immunology and Microbiology Obligate Genetic Variation Toxoplasma gondii 04 agricultural and veterinary sciences General Medicine biology.organism_classification medicine.disease Toxoplasmosis Toxoplasmosis Animal Toxoplasma Polymorphism Restriction Fragment Length |
| Zdroj: | Transboundary and Emerging Diseases. 69:943-957 |
| ISSN: | 1865-1682 1865-1674 |
| Popis: | Toxoplasmosis is one of the most frequent food-borne infections in humans caused by an obligate intracellular protozoan parasite, Toxoplasma gondii. Rodents, as intermediate and reservoir hosts, play key role in the epidemiology of toxoplasmosis; because they are the main source of infection for the Felidae family members and establish the parasite life cycle. Hence, the infectious isolates of T. gondii in rodents may be the main genotypes infecting the environment, humans and animals. Our review aimed to present the population structure of T. gondii in these mammals. To access the relevant studies, six English language databases were systematically searched from 1990 to 2019. Finally, 3,395 samples of rodents were analysed for the genotyping data and 118 isolates were separated from the samples. The results of the present study showed that atypical genotypes were dominant with a frequency of 65.2% of the total isolates (77 out of 118). Clonal Types II, III and I had less frequency, respectively. Type I clonal isolates were identified only from Asia. The examination of genotypes circulating in rodents around the world revealed that ToxoDB #1 or #3 (Type II) were the most common, followed by ToxoDB #9 and #2, respectively. Overall, our data showed low genetic diversity of T. gondii with circulating clonal strains in rodents compare to the isolates from Europe, North America and Africa, while non-clonal parasites with high genetic diversity were dominant in South America and Asia. |
| Databáze: | OpenAIRE |
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