Patient-reported Symptom Burden, Rate of Completion of Palliative Radiotherapy and 30-day Mortality in Two Groups of Cancer Patients Managed With or Without Additional Care by a Multidisciplinary Palliative Care Team
| Autor: | Astrid Dalhaug, Ellinor Haukland, Kirsten Engljähringer, Carsten Nieder |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine Cost of Illness 030502 gerontology Multidisciplinary approach Internal medicine Neoplasms medicine Humans Precision Medicine Depression (differential diagnoses) Survival analysis Aged Retrospective Studies Aged 80 and over Patient Care Team Performance status business.industry Palliative Care Cancer Standard of Care General Medicine Middle Aged medicine.disease Survival Analysis Radiation therapy Oncology Palliative care.team 030220 oncology & carcinogenesis Anxiety Patient Compliance Female Radiotherapy Adjuvant Self Report medicine.symptom 0305 other medical science business |
| Zdroj: | Anticancer research. 38(4) |
| ISSN: | 1791-7530 |
| Popis: | Background/aim The aim of this study was to analyze differences in symptom burden, baseline and outcome parameters, including completion of palliative radiotherapy and 30-day mortality, between patients treated with palliative radiotherapy (RT) who were managed exclusively by regular oncology staff or a multidisciplinary palliative care team (MPCT) in addition. Patients and methods This was a retrospective single-institution analysis. Comparison of two groups of patients: MPCT versus none (n=36 and 65, respectively). All patients provided Edmonton symptom assessment system (ESAS) data before RT. Results The MPCT group included significantly more patients with reduced performance status. Furthermore, these patients had higher ESAS symptom scores, except for two items (dyspnea, sleep). The largest differences were observed for pain, fatigue, anxiety and depression. The significant difference in pain scores was also reflected in different opioid medication rates. Failure to complete radiotherapy was more common in the MPCT group (11 and 2%, respectively, p=0.05). Thirty-day mortality was different, too (28 and 2%, respectively, p=0.0001). The Kaplan-Meier survival curves were not significantly different (1-year survival rates 21 and 25%, respectively, p=0.27). Conclusion The MPCT group was characterized by a higher symptom burden. Prognostic factors such as performance status were not balanced between the two groups. Despite this fact, actuarial overall survival was comparable. Given the high rate of 30-day mortality in the MPCT group, efforts to optimize criteria for initiation of radiotherapy are warranted. |
| Databáze: | OpenAIRE |
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