Use of conditional reprogramming cell, patient derived xenograft and organoid for drug screening for individualized prostate cancer therapy: Current and future perspectives (Review)

Autor:	Jessica, Cao, Wing C, Chan, Moses S S, Chow
Rok vydání:	2022
Předmět:	Male Organoids Disease Models Animal Cancer Research Oncology Drug Evaluation Preclinical Tumor Cells Cultured Animals Heterografts Humans Prostatic Neoplasms Precision Medicine Cellular Reprogramming
Zdroj:	International Journal of Oncology. 60
ISSN:	1791-2423 1019-6439
DOI:	10.3892/ijo.2022.5342
Popis:	Prostate cancer mortality is ranked second among all cancer mortalities in men worldwide. There is a great need for a method of efficient drug screening for precision therapy, especially for patients with existing drug‑resistant prostate cancer. Based on the concept of bacterial cell culture and drug sensitivity testing, the traditional approach of cancer drug screening is inadequate. The current and more innovative use of cancer cell culture and
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d632a8f9645dc9253d7eb12124866b9f https://doi.org/10.3892/ijo.2022.5342 Zobrazit plný text záznamu