Transbulbar B-Mode Sonography in Multiple Sclerosis: Clinical and Biological Relevance
| Autor: | Rocco Scarpello, Antonella Muscella, Roberto De Masi, Stefania Orlando, Sergio Pasca, Aldo Conte, Antonella De Donno, Pantaleo Spagnolo |
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| Přispěvatelé: | De Masi, Roberto, Orlando, Stefania, Conte, Aldo, Pasca, Sergio, Scarpello, Rocco, Spagnolo, Pantaleo, Muscella, Antonella, DE DONNO, Maria Antonella |
| Jazyk: | angličtina |
| Předmět: |
Adult
Male Optic nerve sheath medicine.medical_specialty Acoustics and Ultrasonics Optic nerve Biophysics Multiple sclerosis 03 medical and health sciences 0302 clinical medicine Visual evoked potentials Medicine Humans Multiple sclerosi Radiology Nuclear Medicine and imaging Brain magnetic resonance imaging In patient Clinical significance Evoked potential 10. No inequality Afferent visual pathway Ultrasonography Expanded Disability Status Scale Radiological and Ultrasound Technology business.industry medicine.disease Transbulbar B-mode sonography 3. Good health Surgery Cross-Sectional Studies Radiology Nuclear Medicine and imaging 030221 ophthalmology & optometry Female Radiology business 030217 neurology & neurosurgery |
| Zdroj: | Ultrasound in Medicine & Biology. (12):3037-3042 |
| ISSN: | 0301-5629 |
| DOI: | 10.1016/j.ultrasmedbio.2016.07.018 |
| Popis: | Optic nerve sheath diameter quantification by transbulbar B-mode sonography is a recently validated technique, but its clinical relevance in relapse-free multiple sclerosis patients remains unexplored. In an open-label, comparative, cross-sectional study, we aimed to assess possible differences between patients and healthy controls in terms of optic nerve sheath diameter and its correlation with clinical/paraclinical parameters in this disease. Sixty unselected relapse-free patients and 35 matched healthy controls underwent transbulbar B-mode sonography. Patients underwent routine neurologic examination, brain magnetic resonance imaging and visual evoked potential tests. The mean optic nerve sheath diameter 3 and 5 mm from the eyeball was 22–25% lower in patients than controls and correlated with the Expanded Disability Status Scale (r = −0.34, p = 0.048, and r = −0.32, p = 0.042, respectively). We suggest that optic nerve sheath diameter quantified by transbulbar B-mode sonography should be included in routine assessment of the disease as an extension of the neurologic examination. |
| Databáze: | OpenAIRE |
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