Phytochemistry of Three Ecuadorian Lamiaceae: Lepechinia heteromorpha (Briq.) Epling, Lepechinia radula (Benth.) Epling and Lepechinia paniculata (Kunth) Epling
| Autor: | Jackeline León, Willan Quinche, Lita Benítez, Gianluca Gilardoni, Carlo Bicchi, Vladimir Morocho, Mayra Montalván, Jorge Ramírez, Nixon Cumbicus |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
food.ingredient Ledol guaiol caryophyllene oxide Plant Science 01 natural sciences essential oil law.invention 03 medical and health sciences Lepechinia Camphor chemistry.chemical_compound food law lcsh:Botany spathulenol 5-hydroxy-4′ 7-dimethoxy flavone Ecology Evolution Behavior and Systematics Heteromorpha Essential oil Lamiaceae Ecology biology Traditional medicine 010405 organic chemistry Chemistry Guaiol carnosol Lepechinia paniculata biology.organism_classification 0104 chemical sciences lcsh:QK1-989 ledol angustanoic acid E 030104 developmental biology Ecuador |
| Zdroj: | Plants Volume 8 Issue 1 Plants, Vol 8, Iss 1, p 1 (2018) |
| ISSN: | 2223-7747 |
| DOI: | 10.3390/plants8010001 |
| Popis: | In this research, the leaves of Lepechinia heteromorpha (Briq.) Epling, Lepechinia radula (Benth.) Epling and Lepechinia paniculata (Kunth) Epling have been collected in order to perform a phytochemical study. The first species was distilled to obtain a novel essential oil (EO), while the others were submitted to ethyl acetate extraction and secondary metabolite isolation. The chemical composition of the EO from L. heteromorpha has been investigated by Gas Chromatography-Mass Spectrometry (GC-MS) and Gas Chromatography with Retention Indices (GC(RI)), identifying 25 constituents. A major compound, (&minus )-ledol (21.2%), and a minor compound, (&minus )-caryophyllene oxide (1.0%), were isolated from the EO and their structures confirmed by Nuclear Magnetic Resonance (NMR) spectroscopy. Other major constituents of the EO were viridiflorene (27.3%), (E,E)-&alpha farnesene (1.4%), spirolepechinene and (E)-&beta caryophyllene (7.1% each), allo-aromadendrene (6.1%), camphor (1.7%), limonene (1.3%) and &beta phellandrene (4.6%). The enantiomeric composition of the EO monoterpene fraction was also studied, determining the enantiomeric excess and distribution of &alpha pinene, limonene, &beta phellandrene and camphor. The ethyl acetate extract of L. radula and L. paniculata were fractionated by column chromatography. Spathulenol, angustanoic acid E and 5-hydroxy-4&prime 7-dimethoxy flavone were isolated from L. radula extract ledol, guaiol and (&minus )-carnosol were found in L. paniculata. |
| Databáze: | OpenAIRE |
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