Sentinel surveillance of influenza-like illness in the Central African Republic, 2010–2015

Autor: Marie-Yvette Batoumbou Ketta, Eloi Nicaise Mboufoungou, Emmanuel Nakouné, Eugene Kanga, Kathleen Victoir, Colette Bangue, Sandra Garba-ouangole, Giscard F. Komoyo, Edgar Djimbele, Jean-Chrysostome Gody, Brice Martial Yambiyo, Ombretta Pasotti, Mirdad Kazanji, Alexandre Manirakiza, Ulrich Vickos
Přispěvatelé: Institut Pasteur de Bangui, Réseau International des Instituts Pasteur (RIIP), Complexe pédiatrique, Emergency International [Bangui], Hopital de district de Bossembele, Hôpital secondaire de Boali, Direction Internationale de l'Institut Pasteur, Institut Pasteur [Paris], Institut Pasteur de la Guyane, Sentinel surveillance in the Central African Republic is supported financially by the Department of Health and Human Services, USA., Institut Pasteur [Paris] (IP)
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Archives of Public Health
Archives of Public Health, BioMed Central, 2017, 75 (1), ⟨10.1186/s13690-017-0229-1⟩
Archives of Public Health, Vol 75, Iss 1, Pp 1-7 (2017)
Archives of Public Health, 2017, 75 (1), ⟨10.1186/s13690-017-0229-1⟩
ISSN: 0778-7367
2049-3258
Popis: Background Influenza-like illness (ILI) is an important public health problem worldwide. In the Central African Republic, acute infectious diseases are the commonest reason for consultation. The Institut Pasteur of Bangui set up a surveillance network in 2008 to monitor the circulation of influenza viruses. We report the results of use of this surveillance system during the period 2010–2015. Methods The first surveillance centre covered Bangui, the capital of the country, and neighbouring areas and epidemiological data on syndromes similar to ILI. Throat and nasopharyngeal swab samples are transmitted weekly to the Institut Pasteur of Bangui, where real-time and multiplex reverse transcription polymerase chain reaction are used to detect and subtype influenza A (H1N1 and H3N2) and B viruses. The demographic characteristics of all patients and of positive cases according to age and the seasonal patterns of influenza virus circulation were analysed. Results Between January 2010 and December 2015, 5385 throat swabs were collected; 454 (8.4%) of the samples were positive. Of these, 450 yielded at least one influenza virus and four showed co-infections. Children under the age of 5 years were the most frequently infected (257/450, 57.1%), with irregular peaks of ILI. Influenza B predominated (56.2%; n = 201), with 39.0% H3N2 and 16.7%H1N1pdm09. Influenza viruses were detected mainly in the rainy season (July–December). Conclusion The sentinel surveillance site is yielding important information about the seasonality and age pattern of circulating influenza virus. Nationwide distribution of sentinel sites is warranted.
Databáze: OpenAIRE
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