A cellular and molecular biology-based update for ivermectin against COVID-19: is it effective or non-effective?

Autor: Mohsen Nabi-Afjadi, Fatemeh Mohebi, Hamidreza Zalpoor, Fatemeh Aziziyan, Abdullatif Akbari, Hemen Moradi-Sardareh, Elham Bahreini, Amir Mansour Moeini, Hossein Effatpanah
Rok vydání: 2023
Předmět:
Zdroj: Inflammopharmacology. 31:21-35
ISSN: 1568-5608
0925-4692
Popis: Despite community vaccination against coronavirus disease 2019 (COVID-19) and reduced mortality, there are still challenges in treatment options for the disease. Due to the continuous mutation of SARS-CoV-2 virus and the emergence of new strains, diversity in the use of existing antiviral drugs to combat the epidemic has become a crucial therapeutic chance. As a broad-spectrum antiparasitic and antiviral drug, ivermectin has traditionally been used to treat many types of disease, including DNA and RNA viral infections. Even so, based on currently available data, it is still controversial that ivermectin can be used as one of the effective antiviral agents to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or not. The aim of this study was to provide comprehensive information on ivermectin, including its safety and efficacy, as well as its adverse effects in the treatment of COVID-19.
Databáze: OpenAIRE
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