IN VITRO CYTOTOXICITY OF LYMPHOCYTE SUBPOPULATIONS AGAINST AUTOLOGOUS HUMAN BLADDER TUMOR CELLS
| Autor: | Flemming Jacobsen |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Cytotoxicity Immunologic Male business.industry Effector T-Lymphocytes Lymphocyte Human bladder In vitro cytotoxicity Tumor cells Cell Separation General Medicine Middle Aged Lymphocyte subpopulations medicine.anatomical_structure Urinary Bladder Neoplasms Immunology Humans Medicine Cytotoxic T cell Female Lymphocytes business Cytotoxicity Aged |
| Zdroj: | Acta Pathologica Microbiologica Scandinavica Section C Immunology. :241-246 |
| ISSN: | 0304-1328 |
| DOI: | 10.1111/j.1699-0463.1981.tb02694.x |
| Popis: | The in vitro cytotoxicity of unfractionated blood lymphocytes and T and non-T lymphocytes respectively, was tested against autologous tumor cells from 21 patients with grade III-IV urothelial bladder carcinomas. Generally, little or no cytotoxicity was seen. However, some differences in autologous cytotoxicity between T and non-T lymphocytes were detectable. Four of 21 patients had cytotoxic non-T lymphocytes against autologous bladder tumor cells. The results indicate, that the effector cells are primarily non-T lymphocytes, and that cytotoxicity appears at lower levels of T lymphocytes in unfractionated lymphocyte preparations. |
| Databáze: | OpenAIRE |
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