Yellow Pigments, Fomitellanols A and B, and Drimane Sesquiterpenoids, Cryptoporic Acids P and Q, from Fomitella fraxinea and Their Inhibitory Activity against COX and 5-LO

Autor:	Hiroshi Imagawa, Shigenobu Arihara, Masumi Shimomura, Toshihiro Hashimoto, Kazuko Yoshikawa, Masami Tanaka, Hirofumi Yamamoto, Kazuaki Koso
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Magnetic Resonance Spectroscopy Stereochemistry Pharmaceutical Science Isocitric acid fomitellanol Crystallography X-Ray Article Analytical Chemistry Polyporaceae lcsh:QD241-441 Pigment chemistry.chemical_compound Fomitella fraxinea Lipoxygenase Inhibitors lcsh:Organic chemistry Drug Discovery Cyclooxygenase Inhibitors Physical and Theoretical Chemistry Polycyclic Sesquiterpenes biology Fomitella Organic Chemistry cyclooxygenase-1 (COX-1) and COX-2 Biological activity Nuclear magnetic resonance spectroscopy biology.organism_classification chemistry Chemistry (miscellaneous) visual_art visual_art.visual_art_medium Molecular Medicine 5-lipoxygenase (5-LO) cryptoporic acid Sesquiterpenes
Zdroj:	Molecules, Vol 18, Iss 4, Pp 4181-4191 (2013) Molecules Volume 18 Issue 4 Pages 4181-4191
ISSN:	1420-3049
Popis:	Yellow pigments, fomitellanols A (1a) and B (2a), and drimane-type sesquiterpenoid ethers of isocitric acid, cryptoporic acids P (3) and Q (4), have been isolated from the fruiting bodies of Fomitella fraxinea (Polyporaceae). Their structures were established by a combination of extensive NMR spectroscopy and/or X-ray crystallographic analyses, and their biological activity against COX-1, COX-2, and 5-LO was investigated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d61df47088edc734328ca879d855f175 http://www.mdpi.com/1420-3049/18/4/4181 Zobrazit plný text záznamu Plný text ve formátu PDF