Accuracy in the alteration of acetaminophen suppositories
| Autor: | Tae W. Kim, Cheryl L. Rognerud, Ching Nan Ou |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
business.industry
organic chemicals Suppositories digestive oral and skin physiology Analgesic Analgesics Non-Narcotic digestive system digestive system diseases Acetaminophen Clinical Practice Target dose stomatognathic diseases Anesthesiology and Pain Medicine Liver Anesthesia medicine Humans Antipyretic business Child medicine.drug |
| Zdroj: | Anesthesia and analgesia. 100(5) |
| ISSN: | 0003-2999 |
| Popis: | Many pediatric anesthesiologists divide acetaminophen suppositories to achieve an approximate dose. In this three-part study we first surveyed pediatric anesthesiologists regarding their attitudes and frequency of this clinical practice. Second, acetaminophen suppositories were divided for analysis of acetaminophen content. Finally, the accuracy of pediatric anesthesiologists in dividing suppositories was assessed. The survey indicated 50% of anesthesiologists believed acetaminophen was nonuniform and 62% believed the alteration of suppositories was inaccurate. The laboratory investigation revealed uniform distribution of acetaminophen but poor accuracy in achieving the target dose. The findings suggest using only intact suppositories for improved accuracy. |
| Databáze: | OpenAIRE |
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