Synthesis of Chromen-2-one, Pyrano[3,4-c]chromene and Pyridino[3,4-c]chromene Derivatives as Potent Antimicrobial Agents

Autor:	Amel M. Farrag, Yousry A. Ammar, Sawsan A. Fouad, Samir Y. Abbas, Sadia A. Hessein
Rok vydání:	2018
Předmět:	010405 organic chemistry Chemistry Chromen-2-ones Pyrano[3 4-c]chromenes Pyridino[3 4-c]chromene Antibacterial and antifungal activities Chromen-2-one General Chemistry 010402 general chemistry Antimicrobial 01 natural sciences Combinatorial chemistry 0104 chemical sciences
Zdroj:	Croatica Chemica Acta Volume 91 Issue 1
ISSN:	1334-417X 0011-1643
DOI:	10.5562/cca3266
Popis:	In an attempt for development of new antimicrobial agents; new series of chromen-2-one, pyrano[3,4-c]chromene and pyridino[3,4-c]chromene derivatives bearing a diazo moiety were synthesized. Chromen-2-one derivatives were synthesized via treatment of 5-(aryldiazo) salicylaldehyde with different type of active methylene derivatives. Pyrano[3,4-c]chromene and pyridino[3,4-c]chromene derivatives were synthesized via treatment of chromen-2-one derivatives with another active methylene derivatives. The synthesized compounds were evaluated for their expected antimicrobial activity; where, the majority of these compounds showed potent antibacterial and antifungal activities against the tested strains of bacteria and fungi. This work is licensed under a Creative Commons Attribution 4.0 International License.
Databáze:	OpenAIRE
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