Magnifying gastroendoscopy for diagnosis of histologic gastritis in the gastric antrum
| Autor: | Ken Haruma, Shinji Tanaka, Sun Jin Kim, Masanori Ito, Kazuaki Chayama, Masaharu Yoshihara |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Endoscope Gastroenterology Endoscopy Gastrointestinal Helicobacter Infections Japan Internal medicine Biopsy medicine Pyloric Antrum Humans Antrum Aged Aged 80 and over Hepatology medicine.diagnostic_test biology business.industry Intestinal metaplasia Histology Helicobacter pylori Middle Aged medicine.disease biology.organism_classification Endoscopy Gastritis Female medicine.symptom business |
| Zdroj: | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 36(4) |
| ISSN: | 1590-8658 |
| Popis: | Background. We investigated the potential of magnifying endoscopy for diagnosis of histologic gastritis in the gastric antrum. In addition, we investigated whether magnifying endoscopy can be applied for evaluation of Helicobacter pylori eradication therapy. Methods. We examined 176 Japanese patients including 53 with H. pylori eradication. We evaluated the antrum by magnifying observation and ordinary endoscopic findings, and compared these results. Biopsy specimens were taken from the sites observed. Results. The magnified views were classified into four types. Histology of the biopsy specimens allowed us to match the four magnified views with normal mucosa with fundic glands, normal mucosa with pyloric glands, mucosa with gastritis and intestinal metaplasia/epithelial hyperplasia. The types of magnifying appearances were specific enough for the diagnosis of histologic gastritis (148 out of the 176 (82.4%) cases; sensitivity, 96.3%; specificity, 73.7%). We could accurately diagnose the histologic gastritis by magnifying endoscopy in 49 out of the 53 (92%) cases with H. pylori eradication, while only in 38% by ordinary endoscopy. The accuracy of diagnosis was statistically higher with the use of magnifying endoscopy than with ordinary endoscope (P |
| Databáze: | OpenAIRE |
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