Clinical Application of Chest Computed Tomography (CT) in Detection and Characterization of Coronavirus (Covid-19) Pneumonia in Adults
| Autor: | Doaa T. Masallat, Mohamed N. E. Kassem |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Economic shortage Computed tomography medicine.disease_cause Article 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Stage (cooking) Prospective cohort study Lung Coronavirus Radiological and Ultrasound Technology medicine.diagnostic_test business.industry SARS-CoV-2 COVID-19 medicine.disease Computer Science Applications Pneumonia Radiology Nuclear Medicine and imaging MEDIASTINAL LYMPH NODE ENLARGEMENT Radiology Atypical viral pneumonia business Tomography X-Ray Computed 030217 neurology & neurosurgery Ground glass opacities CT |
| Zdroj: | Journal of Digital Imaging |
| ISSN: | 1618-727X |
| Popis: | To analyze diagnostic accuracy of chest computed tomography (CT) and RT-PCR (real-time polymerase chain reaction) for COVID-19 (coronavirus disease 19) pneumonia in early and progressive stages. To evaluate if combination of chest CT with RT-PCR can supplement the shortage of RT-PCR in diagnosis of COVID-19 pneumonia. We conducted a prospective study on 103 male patients. The study population were divided into two groups; early COVID-19 stage (number = 50 patients, with positive RT-PCR but mild symptoms) and progressive COVID-19 stage (number = 53, positive RT-PCR and sever symptoms including fever > 37.5 °C, cough, and shortness of breath). All patients underwent CT imaging. The early stage included typical category; 34% (17 out of 50 cases), 6% indeterminate category (3 cases), 10% atypical category (5 cases) and 50% (25 cases) were normal CT imaging. The progressive stage included typical category that was further divided to five subgroups; (i) peripheral bilateral lower lobe ground-glass opacity (GGO) in (37.7%), (ii) peripheral bilateral lower lobes GGO with peribronchovascular consolidation and bronchiolar dilatation in (18.8%), (iii) peripheral bilateral lower lobes GGO with crazy paving appearance in (15%), (iv) bilateral diffuse GGO in (18.8%), and (v) peripheral bilateral GGO with mediastinal lymph node enlargement (9.4%). Chest CT imaging could aid to supplement the shortages of PCR for clinically suspected patients of COVID-19 in the epidemic area as CT was positive in 50% of patients. Chest CT is very effective in detecting pulmonary parenchymal abnormalities in the progressive stage of COVID-19 patients in 100%. |
| Databáze: | OpenAIRE |
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