Follow-up examinations after medical treatment of pyometra in cats with the progesterone-antagonist aglepristone
Autor: | Deniz Nak, Yavuz Nak, Bilginer Tuna |
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Přispěvatelé: | Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı., Uludağ Üniversitesi/Veterinerlik Fakültesi., Nak, Deniz, Nak, Yavuz, Tuna, Bilginer, AAH-5494-2021 |
Rok vydání: | 2009 |
Předmět: |
Veterinary sciences
Male Antibiotics Aglepristone Trimethoprim Drug antagonism chemistry.chemical_compound Estrenes Treatment outcome Drug combination Small Animals Antiinfective agent CATS Reproduction Cat Pyometra Anesthesia Female medicine.drug Cat diseases medicine.medical_specialty medicine.drug_class Cat disease Drug therapy combination Article Progesterone Antagonist Pharmacotherapy Anti-bacterial agents Sulfadoxine medicine Animals Adverse effect Estrane derivative Hyperplasia Animal business.industry Animal disease medicine.disease Surgery Gestagen chemistry Subcutaneous drug administration Cats Bitches Deslorelin Injections subcutaneous Progestins business |
Zdroj: | Journal of Feline Medicine and Surgery. 11:499-502 |
ISSN: | 1532-2750 1098-612X |
DOI: | 10.1016/j.jfms.2008.09.006 |
Popis: | The aim of this study was to determine the therapeutic success of the medical treatment of pyometra with the antigestagen aglepristone and to document the recurrence rate in relation to the time interval after treatment with antigestagens in cats. Ten cats, 2–13 years of age and nulliparous were used in the study. The cats were treated with aglepristone at a dose of 10 mg/kg body weight subcutaneously on days 1, 2, 7 and 14 (if not cured). In addition, trimethoprim/sulphadoxine was also administered at a dose of 15 mg/kg body weight subcutaneously once a day for 7 days. Nine out of the 10 cats responded well to treatment. No recurrence was observed in a follow-up period of 2 years. No side effects were observed. The data suggest that aglepristone treatment is a promising approach for the medical treatment of pyometra in cats. |
Databáze: | OpenAIRE |
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