Lip squamous cell carcinoma in a Brazilian population : epidemiological study and clinicopathological associations

Autor: G-T-B Corrêa, R-L Souza, C-M Cardoso, D Sant' Ana-Haikal, F-B-G Santos, A-L-S Guimarães, T Fonseca-Fonseca, A-M-B Batista-De Paula, C-C Oliveira-Santos
Rok vydání: 2011
Předmět:
Zdroj: Souza, Ludmilla Regina ; Fonseca Fonseca, Thiago ; Oliveira Santos, Carolina Carvalho ; Corrêa, Gefter Thiago Batista ; Santos, Francis Balduíno Guimarães ; Cardoso, Cláudio Marcelo ; Sant'ana Haikal, Desiree ; Guimaraes, Andre Luiz Sena ; De Paula, Alfredo Maurício Batista. Lip squamous cell carcinoma in a Brazilian population : epidemiological study and clinicopathological associations. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 16 6 2011: 12
RODERIC. Repositorio Institucional de la Universitat de Valéncia
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Popis: Objectives: It was evaluated epidemiological aspects of primary lip squamous cell carcinoma (LSCC) and its associations with clinicopathological factors. Study design: This retrospective, cross-sectional study analysed a sociodemographic, clinical, and morphological data of HNSCC in a Brazilian population (n=30). Data analysis included descriptive statistics and bivariate analyses using the chi-square and Fisher's exact tests to compare the variables. Results: The LSCC represented 10.8% of all oral cavity squamous cell carcinoma. Lip malignant disease was more prevalent in elderly men, with male-to-female ratio of 5:1. Lower lip was more affected. It was observed high rates of chronic solar exposure, and tobacco and alcohol drinking habits. Clinically, early TNM staging, small tumour lesions, and non-metastatic disease were predominant findings. It was identified a high frequency of well differentiated tumor samples. Worse Karnofsky performance status was associated with cervical metastasis. Conclusions: Our findings showed that LSCC patients exhibited similar epidemiological and clinical profiles as noted in other studies. Still, the occurrence of metastatic disease was associated with a worse physical performance status of the LSCC patients during diagnosis. © Medicina Oral S. L.
Databáze: OpenAIRE