Factors associated with Clostridium difficile infection: A nested case-control study in a three year prospective cohort

Autor:	Nagham, Khanafer, Philippe, Vanhems, Frédéric, Barbut, Christine, Luxemburger, Clarisse, Demont, Monique, Hulin, Olivier, Dauwalder, François, Vandenesch, Laurent, Argaud, Lionel, Badet, Xavier, Barth, Malik, Bertrand, Carole, Burillon, Roland, Chapurlat, Michel, Chuzeville, Brigitte, Comte, François, Disant, Michel Henry, Fessy, Christian, Gouillat, Laurent, Juillard, Patrick, Lermusiaux, Olivier, Monneuse, Emmanuel, Morelon, Jacques, Ninet, Thierry, Ponchon, Emmanuel, Poulet, Thomas, Rimmele, Karim, Tazarourte
Rok vydání:	2017
Předmět:	Adult Diarrhea Male 0301 basic medicine Pediatrics medicine.medical_specialty genetic structures 030106 microbiology Microbiology Hospitals University Young Adult 03 medical and health sciences 0302 clinical medicine Risk Factors Humans Medicine Infection control Prospective Studies 030212 general & internal medicine Prospective cohort study Beta-Lactamase Inhibitors Aged Aged 80 and over Cross Infection Clostridioides difficile business.industry Case-control study Middle Aged Clostridium difficile Anti-Bacterial Agents Infectious Diseases Case-Control Studies Nested case-control study Clostridium Infections Female France medicine.symptom business Cohort study
Zdroj:	Anaerobe. 44:117-123
ISSN:	1075-9964
Popis:	Background Clostridium difficile infection (CDI) is a serious medical condition that is associated with substantial morbidity and mortality. Identification of risk factors associated with CDI and prompt recognition of patients at risk is key to successfully preventing CDI. Methods A 3-year prospective, observational, cohort study was conducted in a French university hospital and a nested case-control study was performed to identify risk factors for CDI. Inpatients aged 18 years or older, suffering from diarrhea suspected to be related to CDI, were asked to participate. Results A total of 945 patients were included, of which 233 cases had a confirmed CDI. CDI infection was more common in men (58.4%) (P = 0.04) compared with patients with diarrhea not related to C. difficile. Previous hospitalization (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e28b193064430274bde735bb385ce4 https://doi.org/10.1016/j.anaerobe.2017.03.003 Zobrazit plný text záznamu Full Text from ScienceDirect