Optimal vaccination policies for stochastic epidemics among a population of households
| Autor: | Owen D. Lyne, Frank Ball |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Statistics and Probability
Family Characteristics Stochastic Processes education.field_of_study Actuarial science General Immunology and Microbiology Applied Mathematics Vaccination Population Models Immunological General Medicine Communicable Diseases Constructive General Biochemistry Genetics and Molecular Biology Modeling and Simulation Influenza Human Economics Humans General Agricultural and Biological Sciences education Mixing (physics) |
| Zdroj: | Mathematical Biosciences. :333-354 |
| ISSN: | 0025-5564 |
| Popis: | This paper considers stochastic epidemics among a population partitioned into households, with mixing locally within households and globally throughout the population. The two levels of mixing have important implications for the threshold behaviour of the epidemic and consequently for the form and construction of optimal vaccination policies. Optimality is considered in terms of the cost of the vaccination program, the form of which is general enough to include costs of the vaccine itself, its administration, travel to and/or contact with the households. New explicit results are obtained by a constructive method which explain the form of optimal vaccination policies. Numerical studies are presented which exemplify the results discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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