Post-therapeutical changes in the brain: novel trends in imaging and their infuence on external beam radiotherapy
| Autor: | E. Bolješíková, V. Belan, B Rychly, M Novotny, P. Kalina, J Steno, I. Makaiová, L Pruzincova, M. Chorváth, V. Pročka |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
In vivo magnetic resonance spectroscopy Cancer Research Magnetic Resonance Spectroscopy medicine.medical_treatment Perfusion scanning Fluorodeoxyglucose F18 Biopsy medicine Humans External beam radiotherapy medicine.diagnostic_test Brain Neoplasms business.industry Brain Cancer Magnetic resonance imaging Glioma Middle Aged medicine.disease Magnetic Resonance Imaging Oncology Positron emission tomography Positron-Emission Tomography Nuclear medicine business Diffusion MRI |
| Zdroj: | Neoplasma. 56:156-162 |
| ISSN: | 0028-2685 |
| DOI: | 10.4149/neo_2009_02_156 |
| Popis: | Presented is the analysis of patients who underwent external beam radiotherapy (EBRT) to the brain in the period from 2003 to 2006 at the department of Radiation Oncology of the St. Elisabeth Cancer Institute.p align="justify"The aim of our analysis was to identify risk factors of late delayed therapy induced injuries (LDTI) in the brain. The patients were regularly examined with magnetic resonance (MRI), including conventional and advanced techniques: perfusion imaging (pMRI), diffusion weighted imaging (DWI), MRI spectroscopy (MRS). The results from MRI were correlated withsup18/supfluoro-deoxyglucose positron emission tomography (sup18/supFDG/PET) scans, as none of the listed method is sufficiently sensitive and specific by itself. Also clinical data records and treatment plans of these patients were analyzed./pp align="justify"In our cohort we found 6 patients with abnormal post-therapeutical changes, 4 of them with MR andsup18/supFDG/PET scans characteristics for LDTI - radiation necrosis. In one patient biopsy was performed and radiation necrosis (RN) was confirmed./pradiation necrosis, MRI, PET, 3D conformal radiotherapy (3D-CRT). |
| Databáze: | OpenAIRE |
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