Clinical course of COVID‐19 in children with pre‐existing medical conditions
| Autor: | Emanuela Piccotti, Elio Castagnola, Marcello Mariani, Giacomo Brisca, Daniela Pirlo, Gioacchino Andrea Rotulo, Marta Romanengo, Andrea Moscatelli |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent MEDLINE Comorbidity Disease Severity of Illness Index Risk Factors Diabetes mellitus Severity of illness medicine Humans Prospective Studies Pediatrics Perinatology and Child Health Child Prospective cohort study Asthma business.industry Mortality rate Infant Newborn COVID-19 Infant General Medicine Prognosis medicine.disease Italy Child Preschool Pediatrics Perinatology and Child Health Disease Progression Female business |
| Zdroj: | Acta Paediatrica |
| ISSN: | 1651-2227 0803-5253 |
| DOI: | 10.1111/apa.15730 |
| Popis: | Children appear to have milder COVID-19 than adults and a more favourable clinical course (1-2). Adult comorbidities, including advanced age, diabetes and cardiovascular disease, have been associated with severe COVID-19 and the highest mortality rates (3). We presume that children with pre-existing conditions face a higher risk from COVID-19 than healthy peers, but studies are scarce and detailed clinical information has often been lacking. Bixler et al studied 121 people under 21 years, whose deaths were associated with COVID-19 and had been reported to the American Centers for Disease Control by 31 July 2020. They found that 75% had at least one underlying medical condition (4) and the most frequent were chronic lung disease, including asthma, and neurological, developmental and cardiovascular conditions. A systematic review by Williams et al reported that paediatric comorbidities increased the risk of critical COVID-19 and cardiac disease was the most common comorbidity (5). |
| Databáze: | OpenAIRE |
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