Metabolic changes during prolonged total parenteral nutrition in intensive care
| Autor: | E. Castelli, C. Cetrullo, M. Zanello |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Parenteral Nutrition
medicine.medical_specialty Physiology Emergency Nursing Hydroxybutyrate Dehydrogenase chemistry.chemical_compound Glutamate Dehydrogenase Liver Function Tests Cholestasis Lactate dehydrogenase Intensive care medicine Humans Aspartate Aminotransferases Child Intensive care medicine Creatine Kinase L-Lactate Dehydrogenase medicine.diagnostic_test biology business.industry Liver Diseases Alanine Transaminase gamma-Glutamyltransferase Jaundice Alkaline Phosphatase medicine.disease Parenteral nutrition chemistry Butyrylcholinesterase Emergency Medicine biology.protein Alkaline phosphatase Parenteral Nutrition Total Creatine kinase medicine.symptom Cardiology and Cardiovascular Medicine Liver function tests business |
| Zdroj: | Resuscitation. 6:235-242 |
| ISSN: | 0300-9572 |
| DOI: | 10.1016/0300-9572(78)90003-5 |
| Popis: | Intensive care patients receiving prolonged total parenteral nutrition (TPN) developed alterations of liver function tests, seen in the activity of certain serum enzymes. Hepatomegaly and jaundice sometimes appeared. The changes in chemical pathology were in serum transaminases activity (GOT, GPT, GDH); alkaline phosphatase and γ-glutamyltranspeptidase as indices of cholestasis; lactate dehydrogenase, hydroxybutyrate dehydrogenase and creatine phosphokinase, as enzymes related to energy metabolism; pseudocholinesterase, as a protein metabolism-related enzyme. The possible causes of these alterations in critically ill patients undergoing TPN are considered and a functional final metabolic interpretation is proposed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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