Plasticity in the adult and neonatal central nervous system
| Autor: | Adrian J. Bower |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Central Nervous System Nervous system Brain development Central nervous system Plasticity Cell Movement Memory Basic research Gangliosides Animals Humans Medicine Glucocorticoids Neurons Neuronal Plasticity business.industry Age Factors Infant Newborn Reflex Vestibulo-Ocular General Medicine Anatomy Functional recovery Rats medicine.anatomical_structure Synapses Reflex Surgery Neurology (clinical) Adaptation business Neuroscience Cell Division |
| Zdroj: | British Journal of Neurosurgery. 4:253-264 |
| ISSN: | 1360-046X 0268-8697 |
| DOI: | 10.3109/02688699008992734 |
| Popis: | The adult nervous system is capable of plastic change; studies have shown that plasticity is part of normal adaptation to daily life as well as being part of the response to trauma. The structural substrates of plastic change are described, and the hypotheses for explaining functional recovery in adults following trauma are reviewed. Events in normal brain development are summarized, and experiments designed to investigate the processes involved are described. The brain of the neonate is a much more plastic structure than that of the adult, both in normal development and in response to trauma. Activity in pathways is an essential component for consolidation of connections, whether normal or compensatory. Experiments which elucidate the mechanisms of axonal/target recognition are described. Recent work on the possible development of therapeutic agents to enhance recovery from trauma, in both adults and neonates, is reviewed. An attempt is made to link the findings from basic research to the clinical field. |
| Databáze: | OpenAIRE |
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