A Correlational Study on Cerebral Microbleeds and Carotid Atherosclerosis in Patients with Ischemic Stroke
| Autor: | Xin-na Zhang, Fang-bo Ning, Yan-yong Guo, Bao-liang Sun, Fangfang Zhao, Zhi-gao Wang, Juan Li, Ai-ling Yu, Zhuan Zhao, Hao-yuan Gao, Yuan Gao |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Carotid atherosclerosis
Carotid Artery Diseases Male medicine.medical_specialty 030204 cardiovascular system & hematology Logistic regression Carotid Intima-Media Thickness Severity of Illness Index Brain Ischemia 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine medicine Humans Mixed group In patient cardiovascular diseases Aged Cerebral Hemorrhage Aged 80 and over business.industry Rehabilitation Significant difference Ultrasonography Doppler Middle Aged Magnetic Resonance Imaging Plaque Atherosclerotic Stroke Logistic Models Correlational study ROC Curve Ischemic stroke Cardiology Surgery Female Neurology (clinical) Thickening Cardiology and Cardiovascular Medicine business 030217 neurology & neurosurgery |
| Zdroj: | Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 27(8) |
| ISSN: | 1532-8511 |
| Popis: | This study aimed to investigate the correlation between cerebral microbleeds and carotid atherosclerosis in patients with ischemic stroke.Patients with ischemic stroke treated in a hospital in China from 2016 to 2017 were enrolled in the study. Based on the results from susceptibility-weighted imaging, the patients were divided into cerebral microbleed and noncerebral microbleed groups. The degree of carotid atherosclerosis was assessed with carotid intima-media thickness (CIMB) and Crouse score of carotid plaque. The details of patients' demographic information, cerebrovascular disease-related risk factors, carotid atherosclerosis indices, cerebral microbleed distribution, and grading were recorded, compared, and analyzed.Logistic regression analysis of the 198 patients showed that CIMB and Crouse score were significantly correlated with the occurrence of cerebral microbleeds. The CIMB thickening group (P = .03) and the plaque group (P = .01) were more susceptible to cerebral microbleeds. In the distribution of cerebral microbleed sites, Crouse scores were the highest in the mixed group and showed a statistically significant difference (P .01). As the degree of carotid atherosclerosis increased, the average number of cerebral microbleeds also increased (P .01). The receiver operating characteristic curve analysis of the carotid atherosclerosis indices showed a statistically significant difference. The CIMB value combined with the Crouse score was the best indicator (P .01).In patients with ischemic stroke, cerebral microbleeds are closely related to carotid atherosclerosis. Active control of carotid atherosclerosis is important to prevent cerebral microbleeds in patients with ischemic stroke. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect