The therapeutic effect of bromocriptine as mesylate and estradiol valerate on serum and blood biochemistry of common quails
| Autor: | Muhammad Imran, Shouqun Jiang, Abdelmotaleb A. Elokil, Hafiz Ishfaq Ahmad, Zain-ul Abideen, Aleem Ahmad Khan, Muhammad Nadeem, Tanveer Majeed |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
Physiology Coturnix SF1-1100 chemistry.chemical_compound Therapeutic index White blood cell Internal medicine IMMUNOLOGY HEALTH AND DISEASE medicine Animals Bromocriptine Mesylates Hematology Estradiol hematology business.industry Therapeutic effect Estradiol valerate Albumin quail General Medicine brotin Animal culture estradiol valerate serum biochemistry medicine.anatomical_structure chemistry Uric acid Animal Science and Zoology business Chickens medicine.drug |
| Zdroj: | Poultry Science, Vol 101, Iss 2, Pp 101552-(2022) Poultry Science |
| ISSN: | 0032-5791 |
| DOI: | 10.1016/j.psj.2021.101552 |
| Popis: | Hematology and serum biochemistry study may provide antique knowledge about the physical status of individuals, making them a valuable tool to differentiate healthy animals from affected animals. We aimed to investigate Steroid safety levels in birds through ex-situ studies at regular therapeutic doses. A total of 100 birds were used for hematology and serum biochemistry. This study was designed into two trials over the summer and winter, each comprised five, ten, fifteen, and twenty days. Each study group was based on five control group birds and 20 experimental group birds. A sum of two groups representing two different Steroids trial groups was treated with therapeutic doses t the stretch of five, ten, fifteen, and twenty days each season. A therapeutic dose of each of the Steroids was given at the rate of three drops two times a day to each bird. Analysis of data reveals that Steroids had severe effects on bird's (Coturnix coturnix) hematological parameters. In most trials, the hematological effects of Bromocriptine as mesylate showed an increase in Red blood cell count and White blood cell count. On the other hand, steroid Estradiol Valerate showed a decrease in these parameters. Effect of steroids on serum biochemistry profile indicate acute damage to vital organs, especially to liver and kidney, indicating an increase in cholesterol, total protein, albumin, urea, and uric acid. The overall effect of steroids on the bird's serum and biochemistry of quails were nearly similar but different only in their intensity. |
| Databáze: | OpenAIRE |
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