Neutralization of Alpha-Staphylotoxin Cytotoxic Effect with Human And Monkey Immune Globulins
| Autor: | Oscar Felsenfeld, Ambhan D. Felsenfeld |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Globulin
biology Staphylococcus Haplorhini Molecular biology General Biochemistry Genetics and Molecular Biology Neutralization Hemolysin Proteins Tissue culture Mycoplasma Immune system Antigen Culture Techniques biology.protein Animals Humans Potency Cytotoxic T cell gamma-Globulins Antibody Staphylococcal Food Poisoning Toxins Biological |
| Zdroj: | Experimental Biology and Medicine. 122:442-446 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-122-31157 |
| Popis: | SummaryStaphylococcal α toxin produced cytopathogenic effect in human embryonic kidney tissue cultures. This effect could be neutralized with whole serum and by the IgG but not by the IgA and IgM fractions of human and other primate sera, whereas these immune globulins interacted with antigen to form a precipitate. The neutralizing potency of the sera was more pronounced in persons with chronic staphylococcal skin lesions. |
| Databáze: | OpenAIRE |
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