Anisakis simplex, a relevant etiologic factor in acute urticaria

Autor: J. M. Diez, M. D. Del Pozo, Ignacio Moneo, M. T. Audicana, I. J. Ansotegui, Daniel Muñoz, M. García, Eduardo Fernández, L. Fernández de Corres, M. Etxenagusia
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Zdroj: Scopus-Elsevier
Popis: Del Pozo MD, Audicana M, Diez JM, Munoz D, Ansotegui IJ, Fernandez E, Garcia M, Etxenagusia M, Moneo I, Fernandez de Corres L. Anisakis simplex, a relevant etiologic factor in acute urticaria. Anisakis simplex, a parasite of fish and cephalopods, can induce IgE-mediated reactions. This study aimed to determine the etiologic role of A. simplex in patients affected by urlicaria/angioedema ‘AE’ or anaphylaxis. We studied 100 adult subjects suffering acute episodes of urticaria/AE, by anamnesis, prick tests with A. simplex and fish-mix extracts, and total and specific IgE to both A. simplex and cod. The following criteria of A. simplex allergy were considered: 1’ urticaria/AE within 6 h after fish ingestion; 2’ specific IgE to A. simplex; 3’ positive prick test to A. simplex extract; 4’ exclusion of other suspected causes. Double-blind, placebo-controlled food challenge was not carried out because ethical considerations forbid challenge with a parasite. Specific IgE to A. simplex‘
Databáze: OpenAIRE