Ionized magnesium concentration during liver transplantation, resection of the liver and cardiac surgery
| Autor: | Wolf R. Külpmann, Albrecht Bornscheuer, Elke Rademacher |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Clinical Biochemistry chemistry.chemical_element Liver transplantation Ionized magnesium Citric Acid Resection Hepatic function Internal medicine medicine Humans Magnesium Cardiac Surgical Procedures Aged Ions business.industry Liver Neoplasms Reproducibility of Results General Medicine Middle Aged Massive transfusion Cardiac surgery Liver Transplantation Endocrinology chemistry Calcium Female Liver function business |
| Zdroj: | Scandinavian journal of clinical and laboratory investigation. Supplementum. 224 |
| ISSN: | 0085-591X |
| Popis: | In this study we investigated three groups of patients, the first undergoing liver transplantation (n = 9), the second resection of the liver (n = 7) and the third cardiac surgery (n = 10) with regard to changes of ionized and total magnesium concentration during operation. Liver transplantation: Ionized magnesium concentration decreased from 0.58 mmol/L to 0.34 mmol/L far below the reference interval (0.49-0.72 mmol/L), whereas total magnesium concentration changed only from 0.78 mmol/L to 0.67 mmol/L (reference interval: 0.65-1.05 mmol/L). Citrate concentration increased from 220 mumol/L to 1925 mumol/L (anhepatic stage) because of massive transfusion of blood products. It was inversely correlated to ionized magnesium concentration. Resection of the liver: There was a decline of ionized magnesium from 0.56 mmol/L to 0.43 mmol/L, which slightly exceeded the decline of total magnesium from 0.74 mmol/L to 0.64 mmol/L. Citrate concentration increased moderately even in cases, when no citrate was administered reflecting reduced hepatic function during operation. Cardiac surgery: Only in patients, to whom citrate but not magnesium was infused, ionized magnesium concentration fell slightly below the reference interval (0.45 mmol/L). In the other patients, to whom magnesium was administered, ionized magnesium concentration was within the reference interval or exceeded it. It is concluded that in patients with impaired hepatic function and/or high citrate load the monitoring of ionized magnesium concentration is mandatory. |
| Databáze: | OpenAIRE |
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