Systolic hypertension and progression of aortic valve calcification in patients with aortic stenosis: results from the PROGRESSA study

Autor: Philippe Pibarot, Lionel Tastet, Jean-Pierre Després, Romain Capoulade, Marie-Annick Clavel, Patrick Mathieu, Mylène Shen, Elisabeth Bédard, Eric Larose, Jean G. Dumesnil, Alexe Tremblay, Abdellaziz Dahou, Marie Arsenault, Yohan Bossé
Rok vydání: 2015
Předmět:
Aortic valve
Male
medicine.medical_specialty
Systolic hypertension
Systole
Comorbidity
030204 cardiovascular system & hematology
Doppler echocardiography
Risk Assessment
Severity of Illness Index
Cohort Studies
03 medical and health sciences
0302 clinical medicine
Internal medicine
Multidetector Computed Tomography
Medicine
Humans
Radiology
Nuclear Medicine and imaging
030212 general & internal medicine
Prospective Studies
Aged
Analysis of Variance
medicine.diagnostic_test
business.industry
Incidence
Calcinosis
General Medicine
Aortic Valve Stenosis
Original Articles
Middle Aged
medicine.disease
Prognosis
Echocardiography
Doppler
Stenosis
medicine.anatomical_structure
Blood pressure
Aortic valve stenosis
Aortic Valve
Hypertension
Multivariate Analysis
cardiovascular system
Cardiology
Disease Progression
Linear Models
Female
Aortic valve calcification
Cardiology and Cardiovascular Medicine
business
Zdroj: European heart journal. Cardiovascular Imaging. 18(1)
ISSN: 2047-2412
Popis: Aims Hypertension is highly prevalent in patients with aortic stenosis (AS) and is associated with worse outcomes. The current prospective study assessed the impact of systolic hypertension (SHPT) on the progression of aortic valve calcification (AVC) measured by multidetector computed tomography (MDCT) in patients with AS. Methods and results The present analysis includes the first series of 101 patients with AS prospectively recruited in the PROGRESSA study. Patients underwent comprehensive Doppler echocardiography and MDCT exams at baseline and after 2-year follow-up. AVC and coronary artery calcification (CAC) were measured using the Agatston method. Patients with SHPT at baseline (i.e. systolic blood pressure ≥140 mmHg; n = 37, 37%) had faster 2-year AVC progression compared with those without SHPT (i.e. systolic blood pressure
Databáze: OpenAIRE
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