Phylogenetic Analysis of Nuclear-Encoded RNA Maturases
| Autor: | S. M. Paul Khurana, KC Upadhyaya, Sunita Malik |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0106 biological sciences
0301 basic medicine Nuclear gene Sequence analysis lcsh:Evolution Computational biology Biology 01 natural sciences 03 medical and health sciences splicing Phylogenetics Gene expression nuclear maturases Genetics lcsh:QH359-425 BLAST Maturases Ecology Evolution Behavior and Systematics Original Research Phylogenetic tree fungi RNA food and beverages homology Group II intron Computer Science Applications 030104 developmental biology RNA splicing 010606 plant biology & botany |
| Zdroj: | Evolutionary Bioinformatics Evolutionary Bioinformatics, Vol 13 (2017) |
| ISSN: | 1176-9343 |
| Popis: | Posttranscriptional processes, such as splicing, play a crucial role in gene expression and are prevalent not only in nuclear genes but also in plant mitochondria where splicing of group II introns is catalyzed by a class of proteins termed maturases. In plant mitochondria, there are 22 mitochondrial group II introns. matR, nMAT1, nMAT2, nMAT3, and nMAT4 proteins have been shown to be required for efficient splicing of several group II introns in Arabidopsis thaliana. Nuclear maturases (nMATs) are necessary for splicing of mitochondrial genes, leading to normal oxidative phosphorylation. Sequence analysis through phylogenetic tree (including bootstrapping) revealed high homology with maturase sequences of A thaliana and other plants. This study shows the phylogenetic relationship of nMAT proteins between A thaliana and other nonredundant plant species taken from BLASTP analysis. |
| Databáze: | OpenAIRE |
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