CD117- and vimentin-positive telocytes in the bovine teat sphincter
Autor: | M. G. Wagener, J.‐D. Häger, Christiane Pfarrer, S. Leonhard‐Marek |
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Rok vydání: | 2018 |
Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty animal structures Vimentin Contractility 03 medical and health sciences Mammary Glands Animal Smooth muscle medicine Animals Telocytes Close contact Papillary duct General Veterinary biology CD117 General Medicine medicine.disease Mastitis Proto-Oncogene Proteins c-kit 030104 developmental biology medicine.anatomical_structure biology.protein Sphincter Cattle Female |
Zdroj: | Anatomia, Histologia, Embryologia. 47:268-270 |
ISSN: | 0340-2096 |
Popis: | Mastitis is a common economically relevant problem in dairy farming. As the major entry for pathogens is the papillary duct, one of the first defence mechanisms is the teat sphincter. This sphincter shows a rhythmic contractility of yet unknown origin. Searching for possible modulatory pacemaker cells, teat sphincters of eight cows were stained immunohistochemically with antibodies against CD117 and vimentin and evaluated microscopically for the presence of telocytes. CD117- and vimentin-positive telocytes with telopodes were found in close contact with smooth muscle cells. Our findings present a first evidence of telocytes in the teat of bovines. |
Databáze: | OpenAIRE |
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