Clinical presentation and markers of cutaneous versus systemic mastocytosis: the mastocytosis center at brigham and women's hospital in Boston
| Autor: | Pedro Giavina-Bianchi, Kelly Yoshimi Kanamori, Nathalia Pessoa Simis, Cem Akin, Mariana Castells |
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| Jazyk: | angličtina |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Allergy biology business.industry Cutaneous Mastocytosis Immunology Tryptase medicine.disease Dermatology medicine.anatomical_structure Meeting Abstract biology.protein Medicine Organ involvement Immunology and Allergy Bone marrow Systemic mastocytosis business Anaphylaxis |
| Zdroj: | The World Allergy Organization Journal |
| ISSN: | 1939-4551 |
| DOI: | 10.1186/1939-4551-8-s1-a141 |
| Popis: | Background Mastocytosis is a group of heterogeneous diseases characterized by an abnormal expansion and accumulation of mast cells (MCs) in different tissues. While systemic mastocytosis (SM) is defined by the accumulation of MCs in bone marrow (BM) and different tissues, cutaneous mastocytosis (CM) is characterized as an accumulation of MC in the skin with no other organ involvement. How gender differences, tryptase levels and episodes of anaphylaxis affect cutaneous versus systemic mastocytosis is not well understood. |
| Databáze: | OpenAIRE |
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