Screening of aphrodisiac property in sea slug, Aplysia dactylomela

Autor: Jamaluddin Mohd Daud, Noor Atika Elliyana Mohd Roslan, Farah Hanis Zulkipli, Ridzwan Hashim
Rok vydání: 2014
Předmět:
Zdroj: Asian Pacific Journal of Tropical Medicine. 7:S150-S154
ISSN: 1995-7645
DOI: 10.1016/s1995-7645(14)60222-4
Popis: ObjectiveTo evaluate the aphrodisiac property of Aplysia dactylomela (A. dactylomelan), locally known as ‘dugu-dugu’, which is one of the sea slug species.MethodsTwo types of extractions were used; aqueous and lipid. Three doses of each A. dactylomelan extract, respectively; 50, 100, 200 mg/kg were administered (i.p.) to male mice for mounting behavior test. Sildenafil citrate or Viagra® (5 mg/kg) being positive control while negative control received saline solution.ResultsThe animals treated with lipid extract at the respective dose exhibited mounting behavior, but the mounting frequency decreased at higher doses (100 and 200 mg/kg). However, all doses of aqueous extract did not show any mounting behavior. Meanwhile, in all doses of lipid extracts administered displayed significant difference (P
Databáze: OpenAIRE