Sensitive Electrochemiluminescence Biosensor Based on the Target Trigger Difference of the Electrostatic Interaction between an ECL Reporter and the Electrode Surface

Autor:	Yilei Lu, Xiujun Rong, Peng Wu, Jian Shou, Long Chen, Fang Luo, Cuiying Lin, Jian Wang, Bin Qiu, Zhenyu Lin
Rok vydání:	2022
Předmět:	Luminescent Measurements Static Electricity Humans Biosensing Techniques DNA Electrochemical Techniques Silicon Dioxide Electrodes Analytical Chemistry
Zdroj:	Analytical Chemistry. 94:5823-5829
ISSN:	1520-6882 0003-2700
DOI:	10.1021/acs.analchem.1c05258
Popis:	The discrepancy of the electrostatic interaction of negatively charged signal molecules to long and short DNA strands of the modified electrode surface has been used for the first time to the develop an electrochemiluminescence (ECL) biosensor for human papillomavirus 16 (HPV 16) DNA detection. The short single-stranded capture probe (CP) was modified first on the surface of the gold electrode, which only has a small amount of negative charge. The electrostatic interaction between the negatively charged tris(2,2'-bipyridyl) ruthenium(II) chloride hexahydrate-doped SiO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b4189673fa8e098aad1189a9d4f44e https://doi.org/10.1021/acs.analchem.1c05258 Zobrazit plný text záznamu