Does Sotalol Still Have a Role in the Management of Arrhythmias?
| Autor: | Selvanayagam Niranjan, Selvanayagam Nirthanan, Sahan P. Semasinghe Bandaralage |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Tachycardia
medicine.medical_specialty Torsades de pointes 030204 cardiovascular system & hematology Right ventricular cardiomyopathy Coronary artery disease 03 medical and health sciences 0302 clinical medicine Recurrence Torsades de Pointes Internal medicine Atrial Fibrillation medicine Secondary Prevention Tachycardia Supraventricular Humans Pharmacology (medical) cardiovascular diseases 030212 general & internal medicine Cardiac Surgical Procedures Arrhythmogenic Right Ventricular Dysplasia Pharmacology business.industry Sotalol Atrial fibrillation General Medicine medicine.disease Arrhythmogenic right ventricular dysplasia Treatment Outcome cardiovascular system Cardiology medicine.symptom business Anti-Arrhythmia Agents medicine.drug |
| Zdroj: | American journal of therapeutics. 26(1) |
| ISSN: | 1536-3686 |
| Popis: | Despite proven effectiveness in treating tachyarrhythmias, sotalol is proarrhythmic and can cause torsades de pointes. Given the emergence of studies that show no benefit from rhythm control strategies in managing atrial fibrillation, as well as the introduction of nonpharmacological approaches to treating arrhythmias, we felt it necessary to ascertain if there was any role for sotalol given its side effects. Review of the literature regarding sotalol use in the prevention and treatment of supraventricular and ventricular tachyarrhythmias seems to show that more effective and safer agents and nonpharmacological alternatives are currently available. However, sotalol still seems to be useful in preventing supraventricular tachyarrhythmias postcardiac surgery and in reverting hemodynamically stable sustained ventricular tachycardias in the setting of coronary artery disease. Its role in the prevention of tachyarrhythmias in the setting of arrhythmogenic right ventricular cardiomyopathy requires further investigation. |
| Databáze: | OpenAIRE |
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