First influenza season after the 2009 pandemic influenza: characteristics of intensive care unit admissions in adults and children in Vall d'Hebron Hospital
| Autor: | César Laborda, Marcos Pérez, M. Pujol, Jéssica Souto, Jordi Rello, Garyphallia Poulakou, M. Palomar, Oriol Roca, Joan Balcells, T. Tórtola |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Pediatrics Time Factors Exacerbation medicine.disease_cause law.invention Pulmonary Disease Chronic Obstructive Influenza A Virus H1N1 Subtype Interquartile range law Epidemiology Odds Ratio Prevalence Influenza A virus Prospective Studies Child ICU admission Coinfection Vaccination Bacterial Infections General Medicine Middle Aged Intensive care unit Hospitals Hospitalization Intensive Care Units Infectious Diseases Child Preschool Bronchitis Female Seasons influenza primary viral pneumonia Adult Microbiology (medical) medicine.medical_specialty Adolescent Pneumonia Viral Young Adult Influenza Human medicine Humans Pandemics Asthma Bacteria business.industry Infant medicine.disease H1N1 (2009) Radiography Influenza B virus Spain Bronchiolitis business |
| Zdroj: | Clinical Microbiology and Infection. 18(4):374-380 |
| ISSN: | 1198-743X |
| DOI: | 10.1111/j.1469-0691.2011.03617.x |
| Popis: | To assess potential differences in epidemiology and management of patients admitted with influenza infection in the intensive care unit (ICU) during the first post-pandemic influenza period. Observational prospective study comparing September 2009–January 2010 with September 2010–January 2011. Variables captured: demographics, co-morbidities, physiological parameters, outcomes and management. Analysis was performed using SPSS v. 13.0; significance was set at p 0.5. Data from 53 patients, 38 adults (age, median 41.5 years; interquartile range (IQR) 32.8–51.3) and 15 children (age, median 2 years, IQR 0.5–9) are presented. Vaccination rates were 0% and 4.3% during the first and second periods, respectively. Differences postpandemic were: 100% of episodes developed after December compared with 16.7% in the 2009 season. Younger children were affected (median age 0.8 years (IQR 0.3–4.8) vs 7 years (IQR 1.25–11.5), p 0.05) and influenza B caused 8.7% of ICU admissions. Influenza A (H1N1) 2009 and respiratory syncytial virus epidemics occurred simultaneously (42.8% of children) and bacterial co-infections doubled (from 10% to 21.7%); the prevalence of co-infections (viral or bacterial) increased from 10% to 39.1% (OR 5.8, 95% CI 1.3–24.8). Respiratory syndromes without chest X-ray opacities reflecting exacerbation of asthma or chronic obstructive pulmonary disease, bronchitis or bronchiolitis increased (from 6.9% to 39.1%, p |
| Databáze: | OpenAIRE |
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