Marine Pharmacology in 2014–2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action
| Autor: | Orazio Taglialatela-Scafati, Aimee J Guerrero, Abimael D. Rodríguez, Nobuhiro Fusetani, Fumiaki Nakamura, Alejandro M. S. Mayer |
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| Přispěvatelé: | Mayer, Alejandro M. S., Guerrero, Aimee J., Rodríguez, Abimael D., TAGLIALATELA SCAFATI, Orazio, Nakamura, Fumiaki, Fusetani, Nobuhiro |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Antifungal
Drug natural product Antifungal Agents chemical medicine.drug_class media_common.quotation_subject Oceans and Seas metabolite Anti-Inflammatory Agents Antiprotozoal Agents Antitubercular Agents Pharmaceutical Science Review Pharmacology 01 natural sciences Antiviral Agents Nervous System Anti-inflammatory chemistry.chemical_compound Immune system Drug Discovery medicine pharmaceutical Animals Humans Hypoglycemic Agents Anthelmintic Pharmacology Toxicology and Pharmaceutics (miscellaneous) media_common Anthelmintics Biological Products Natural product 010405 organic chemistry business.industry Preclinical pharmacology drug marine pipeline Anticoagulants 0104 chemical sciences 010404 medicinal & biomolecular chemistry chemistry Immune System Antiprotozoal pharmacology business medicine.drug toxicology |
| Zdroj: | Marine Drugs |
| ISSN: | 1660-3397 |
| Popis: | The systematic review of the marine pharmacology literature from 2014 to 2015 was completed in a manner consistent with the 1998–2013 reviews of this series. Research in marine pharmacology during 2014–2015, which was reported by investigators in 43 countries, described novel findings on the preclinical pharmacology of 301 marine compounds. These observations included antibacterial, antifungal, antiprotozoal, antituberculosis, antiviral, and anthelmintic pharmacological activities for 133 marine natural products, 85 marine compounds with antidiabetic, and anti-inflammatory activities, as well as those that affected the immune and nervous system, and 83 marine compounds that displayed miscellaneous mechanisms of action, and may probably contribute to novel pharmacological classes upon further research. Thus, in 2014–2015, the preclinical marine natural product pharmacology pipeline provided novel pharmacology as well as new lead compounds for the clinical marine pharmaceutical pipeline, and thus continued to contribute to ongoing global research for alternative therapeutic approaches to many disease categories. |
| Databáze: | OpenAIRE |
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